Neonates (including those premature neonates born at 32 weeks gestational age or later, up to 28 days chronological age): 12.5 mg/kg IV every 6 hours For the management of mild to moderate pain and for the management of moderate to severe pain when used with adjunctive opioid analgesics.For IV administration, verify the dose in mg and mL to ensure the dose is correct verify that infusion pumps are properly programmed.Weight: 32.7 to 43.2 kg (11 to 12 years): 480 mg orally every 4 hours as needed not to exceed 5 doses in 24 hoursĪge: 6 to 11 months: 80 mg rectally every 6 hours up to a maximum of 4 doses in 24 hoursĪge: 12 to 36 months: 80 mg rectally every 4 to 6 hours up to a maximum of 5 doses in 24 hoursĪge: 3 to 6 years: 120 mg rectally every 4 to 6 hours up to a maximum of 5 doses in 24 hoursĪge: 6 to 12 years: 325 mg rectally every 4 to 6 hours up to a maximum of 5 doses in 24 hoursĪge: 12 years or older: 650 mg rectally every 4 to 6 hours up to a maximum of 6 doses in 24 hours Weight: 27.3 to 32.6 kg (9 to 10 years): 400 mg orally every 4 hours as needed not to exceed 5 doses in 24 hours Weight: 21.8 to 27.2 kg (6 to 8 years): 320 mg orally every 4 hours as needed not to exceed 5 doses in 24 hours Weight: 16.4 to 21.7 kg (4 to 5 years): 240 mg orally every 4 hours as needed not to exceed 5 doses in 24 hours Weight: 10.9 to 16.3 kg (2 to 3 years): 160 mg orally every 4 hours as needed not to exceed 5 doses in 24 hours Weight: 8.2 to 10.8 kg (12 to 23 months): 120 mg orally every 4 hours as needed not to exceed 5 doses in 24 hours Weight: 5.4 to 8.1 kg (4 to 11 months): 80 mg orally every 4 hours as needed not to exceed 5 doses in 24 hours Weight: 2.7 to 5.3 kg (0 to 3 months): 40 mg orally every 4 hours as needed not to exceed 5 doses in 24 hours Alternatively, use weight first, then age:.ORAL: 10 to 15 mg/kg orally every 4 to 6 hours as needed not to exceed 5 doses in 24 hours Weight 50 kg or greater: 650 mg IV every 4 hours OR 1000 mg IV every 6 hours.Maximum Daily Dose: 75 mg/kg in 24 hours not to exceed 3750 mg Maximum Single Dose: 15 mg/kg not to exceed 750 mg Weight less than 50 kg: 12.5 mg/kg IV every 4 hours OR 15 mg/kg IV every 6 hours.Maximum Daily Dose: 75 mg/kg in 24 hours not to exceed 3750 mg.
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